Monday, 21 July 2014

Mesothelioma Survival Rates

About 40 percent of patients with mesothelioma survive the first year after diagnosis. That survival rate depends on many factors, including age, cancer stage, cancer type, race and gender. Long-term survivors attribute their success to treatment from a mesothelioma specialist, alternative medicine and nutritional changes.

How is survival rate measured?




Incidence of mesothelioma has been found to be higher in populations living near naturally occurring asbestos. For example, in central Cappadocia, Turkey, mesothelioma was causing 50% of all deaths in three small villages—Tuzköy, Karain and Sarıhıdır. Initially, this was attributed to erionite, a zeolite mineral with similar properties to asbestos. Similar "epidemics" have occurred in the past in Metsovo, (North West Greece) and other Mediterrenean countries (Cyprus, Corsica) but also as far as New Caledonia in the Pacific Ocean.[22] In all these areas, the incriminating agent was asbestos (usually tremolite used as whitewash). In Metsovo, this exposure had resulted in mesothelioma incidence around 300 times more than expected in asbestos free populations and was associated with very frequent Pleural Calcification known as "Metsovo Lung". Recently, however, detailed epidemiological investigation showed that erionite causes mesothelioma mostly in families with a genetic predisposition.[23][24] The documented presence of asbestos fibers in water supplies and food products has fostered concerns about the possible impact of long-term and, as yet, unknown exposure of the general population to these fibers.

Occupational[edit]

Exposure to asbestos fibers has been recognized as an occupational health hazard since the early 20th century. Numerous epidemiological studies have associated occupational exposure to asbestos with the development of pleural plaques, diffuse pleural thickening, asbestosis, carcinoma of the lung and larynx, gastrointestinal tumors, and diffuse malignant mesothelioma of the pleura and peritoneum. Asbestos has been widely used in many industrial products, including cement, brake linings, gaskets, roof shingles, flooring products, textiles, and insulation.
Commercial asbestos mining at Wittenoom, Western Australia, occurred between 1945 and 1966. A cohort study of miners employed at the mine reported that while no deaths occurred within the first 10 years after crocidolite exposure, 85 deaths attributable to mesothelioma had occurred by 1985. By 1994, 539 reported deaths due to mesothelioma had been reported in Western Australia.

Paraoccupational secondary exposure[edit]

Family members and others living with asbestos workers have an increased risk of developing mesothelioma, and possibly other asbestos related diseases.[25][26] This risk may be the result of exposure to asbestos dust brought home on the clothing and hair of asbestos workers. To reduce the chance of exposing family members to asbestos fibres, asbestos workers are usually required to shower and change their clothing before leaving the workplace.

Asbestos in buildings[edit]

Many building materials used in both public and domestic premises prior to the banning of asbestos may contain asbestos. Those performing renovation works or DIY activities may expose themselves to asbestos dust. In the UK use of Chrysotile asbestos was banned at the end of 1999. Brown and blue asbestos was banned in the UK around 1985. Buildings built or renovated prior to these dates may contain asbestos materials.

Genetic disposition[edit]

In a recent research carried on white American population in 2012, it was found that people with a germline mutation on their BAP1 gene are at higher risk of developing mesothelioma and uveal melanoma.[27]

Source:- https://en.wikipedia.org/?title=Mesothelioma

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